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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1A1L
All Species:
37.58
Human Site:
S242
Identified Species:
59.05
UniProt:
Q8N752
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N752
NP_660204.1
337
39086
S242
K
I
S
E
K
K
M
S
T
P
V
E
V
L
C
Chimpanzee
Pan troglodytes
XP_522662
337
39019
S242
K
I
S
E
K
K
V
S
T
P
V
E
V
L
C
Rhesus Macaque
Macaca mulatta
XP_001085343
337
38964
S242
K
I
S
E
K
K
M
S
T
P
V
E
V
L
C
Dog
Lupus familis
XP_867638
336
38749
S242
K
I
S
E
K
K
M
S
T
P
V
E
V
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
E315
R
R
E
H
E
R
E
E
R
M
G
Q
L
R
G
Rat
Rattus norvegicus
P97633
325
37477
E234
A
T
K
K
Q
K
Y
E
K
I
S
E
K
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P67962
337
38882
S242
K
I
S
E
K
K
M
S
T
P
V
E
V
L
C
Frog
Xenopus laevis
Q5BP74
415
47421
L315
R
R
E
R
E
E
R
L
R
H
T
R
N
P
A
Zebra Danio
Brachydanio rerio
Q7T2E3
403
46225
F273
Y
S
Y
L
R
Q
L
F
R
N
L
F
H
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54367
337
39516
S245
K
I
S
E
K
K
M
S
T
P
I
E
V
L
C
Honey Bee
Apis mellifera
XP_393612
350
40282
S246
K
I
S
E
K
K
M
S
T
P
V
E
V
L
C
Nematode Worm
Caenorhab. elegans
P42168
341
39018
T241
K
I
S
E
K
K
M
T
T
S
V
E
H
L
C
Sea Urchin
Strong. purpuratus
XP_786391
348
40003
S256
K
I
S
E
K
K
M
S
T
P
V
E
V
L
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
F273
Y
A
Y
L
K
R
I
F
R
D
L
F
I
R
E
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
S376
I
L
N
N
N
A
A
S
S
L
P
E
E
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.9
90.5
N.A.
54.5
88.1
N.A.
N.A.
90.5
53.9
56.5
N.A.
70.6
76.2
75.3
74.1
Protein Similarity:
100
99.6
99.4
94.3
N.A.
66.1
91
N.A.
N.A.
94.6
66
68.2
N.A.
81.3
84
82.1
84.2
P-Site Identity:
100
93.3
100
100
N.A.
0
13.3
N.A.
N.A.
100
0
0
N.A.
93.3
100
80
100
P-Site Similarity:
100
100
100
100
N.A.
33.3
26.6
N.A.
N.A.
100
20
26.6
N.A.
100
100
86.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.6
39.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.7
52.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
7
7
0
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% D
% Glu:
0
0
14
60
14
7
7
14
0
0
0
74
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
14
0
0
0
14
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% G
% His:
0
0
0
7
0
0
0
0
0
7
0
0
14
0
0
% H
% Ile:
7
60
0
0
0
0
7
0
0
7
7
0
7
0
0
% I
% Lys:
60
0
7
7
67
67
0
0
7
0
0
0
7
7
0
% K
% Leu:
0
7
0
14
0
0
7
7
0
7
14
0
7
67
7
% L
% Met:
0
0
0
0
0
0
54
0
0
7
0
0
0
0
7
% M
% Asn:
0
0
7
7
7
0
0
0
0
7
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
54
7
0
0
7
0
% P
% Gln:
0
0
0
0
7
7
0
0
0
0
0
7
0
0
7
% Q
% Arg:
14
14
0
7
7
14
7
0
27
0
0
7
0
20
0
% R
% Ser:
0
7
60
0
0
0
0
60
7
7
7
0
0
0
0
% S
% Thr:
0
7
0
0
0
0
0
7
60
0
7
0
0
0
0
% T
% Val:
0
0
0
0
0
0
7
0
0
0
54
0
54
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
0
14
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _